The brain–gut–microbiome network in metabolic regulation and dysregulation
Wednesday 10th October
15:00 – 16.00 Bus arrives and cold lunch
16:00 – 16:10 Welcome
16:10 – 18:10 Cross-talk between the gut and the brain in metabolic regulation (Chair: Stephane Schurmans)
16:10 – 16:50 Jarrad M.Scarlett, University of Washington. Seattle, USA
Role of the brain in the pathogenesis of obesity, insulin resistance and type 2 diabetes.
16:50 – 17:30 Shiho Fujisaka, University of Toyama, Japan
Interaction between the gut microbiota and metabolites in insulin resistance and metabolic syndrome.
17:30 – 18:10 Amandine Everard, UCL, Brussels, Belgium
Cross-talk between the gut microbiota and the brain during metabolic disorders.
18:10 – 18:50 Vassilis Pachnis, Francis Crick Institute, London, UK
Control of the gastrointestinal tract by the enteric neuronal system.
19:00 – 20:30 Dinner
20:30 – 21:30 The first Jacques E. Dumont keynote lecture (Chair: Nathalie Delzenne)
Jens Juul Holst, University of Copenhagen, Denmark
The endocrine function of the gut.
21:30 Poster session
Thursday 11th October
8:30 – 13:00 The gut microbiota: a complex ecosystem and its interaction with host cells (Chair: Stefan Offermanns)
8:30 – 9:10 Colin Hill, University College Cork, Ireland
Overview of gut bacteriophages and their role in shaping the microbiome.
9:10 – 9:50 Oluf B. Pedersen, University of Copenhagen, Denmark
Human gut microbes impact host serum metabolome and insulin sensitivity.
9:50 – 10:30 Eran Elinav, Weizmann Institute, Jerusalem, Israel
Environmental, nutritional and endogenous modulation of the microbiota.
10:30 – 11:00 Coffee break
11:00 – 11:40 Siegfried Ussar, Helmholtz Diabetes Center, München, Germany
Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome.
11:40 – 12:20 Peter Holzer, University of Graz, Austria
Gut – brain – microbiome interactions in obesity and depression.
12:20 – 13:00 Two short talks from abstracts.
13:00 – 14:30 Lunch
14:30 – 16:30 Walk around Mt Ste Odile
16:30 – 19:10 New mediators/targets in gut function (Chair: Veit Flockerzi)
16:30 – 17:10 Bart Staels, Institut Pasteur, Lille, France
Bile acids as metabolic regulators of endocrine function and energy metabolism.
17:10 – 17:50 Ellen Blaak, Maastricht University, The Netherlands
Short chain fatty acids as mediators of host energy metabolism.
17:50 – 18:30 Gilles Mithieux, INSERM, Lyon, France
Regulation of intestinal gluconeogenesis: which consequences for neuroendocrine function and energy metabolism?
18:30 – 20:00 Dinner
20:00 – 21:00 Keynote lecture (Chair: Pierre De Meyts)
Karine Clément, Pitié-Salpêtrière, Paris, France
Organ cross-talk in the pathophysiology of obesity
21:00 Poster session
Friday 12th October
8:30 - 12:30 The gut microbiome in metabolic regulation and dysregulation across lifespan (Chair: Adriana Maggi)
8:30 – 9:10 Herbert Tilg, Medical University, Innsbrück, Austria
Gut dysfunction and non-alcoholic fatty liver
9:10 – 9:50 Louise Olofsson, Salghrenska Academy, University of Göteborg, Sweden
Mechanistic studies of the impact of the gut microbiome on obesity and type 2 diabetes.
9:50 – 10:30 Remy Burcelin, INSERM, Paul Sabatier University, Toulouse, France.
Gut barrier and bacterial translocation in metabolic diseases.
10:30 – 11:00 Coffee break
11:00 – 11:40 Joël Doré, Metagenopolis, INRA, Paris, France
Do metagenomics approaches in cohorts support a key role for gut microbiome in metabolic diseases?
11:40 – 12:20 Two short talks selected from abstracts
12:30 – 14:00 Lunch
14:00 - 14:40 Patrizia Brigidi, University of Bologna, Italy
The gut microbiota of centenarians: signatures of longevity in the gut microbiota profiles.
14:40 – 18:00 The gut microbiome and CNS dysfunction (Chair: Jean-Philippe Pin)
14:40 – 15:20 Tristan Bolmont, Stemedica International, Lausanne, Switzerland
Gut microbiota alterations in Alzheimer’s disease: from preclinics to clinical studies.
15:20 – 15:50 Coffee break
15:50 – 16:30 Sylvie Claeysen, INSERM U661, University of Montpellier, France
Microbiota influence on Alzheimer’s development
16:30 – 17:10 Helen Vuong, UCLA, Los Angeles, USA
Maternal microbiome and neurodevelopment.
17:10 – 17:40 John Cryan, University College Cork, Ireland
Gut-brain axis revisited: which role for the gut microbiota in mood and depression?
17:40 – 18:00 Short talk selected from abstracts.
18:00 – 19:00 Keynote lecture (Chair: Maria Sibilia)
Emrah Altindis, Joslin Diabetes Center, Boston, USA
Viral insulin like peptides activate insulin and IGF-I receptor signalling: a paradigm shift in host microbe interactions.
19:00 – 21:00 Wine tasting and gala dinner
21:00 Posters session
Saturday 13th October
9:00 – 11:40 Therapeutic perspectives (Chair: David Carling)
9:00 – 9:40 Filipe Cabreiro, UCL, London, UK
Effects of drug-nutrient-microbe interactions on host physiology and lifespan.
9:40 – 10:20 Nathalie Delzenne, UCL, Brussels, Belgium
Feeding the gut microbiota with prebiotic dietary fibers: therapeutic interest in metabolic disorders.
10:20 – 10:50 Coffee break
10:50 – 11:30 Max Nieuwdorp, Akademisch Medisch Centrum, University of Amsterdam, The Netherlands
Gut microbial transfer from healthy to diseased (T2D) individuals.
11:30 – 12:30 Keynote lecture (Chair: Jacques E. Dumont)
Hubert Vidal, CarMeN laboratory, INSERM U1060, University of Lyon, France.
Development of new probiotics for the treatment of diabetes/insulin resistance.
13:30 Bus transfer