Guidelines

About our Guidelines

The European Society of Endocrinology is a focal point for endocrinology and hormone research in Europe. We collaborate with national and specialty societies, and champion endocrinology at a pan-European level. The Society will also consider endorsement requests for other organisations guidelines.

Partner Guideline: International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome 2023

Authors: Helena J Teede, Chau Thien Tay, Joop J E Laven, Anuja Dokras, Lisa J Moran, Terhi T Piltonen, Michael F Costello, Jacky Boivin, Leanne M Redman, Jacqueline A Boyle, Robert J Norman, Aya Mousa, Anju E Joham on behalf of the International PCOS Network.

European Society of Endocrinology Clinical Practice Guideline on the management of Adrenal Incidentalomas, in collaboration with the European Network for the Study of Adrenal Tumors

A comprehensive revision of the 2016 Guideline on management of adrenal incidentalomas, that incorporates the most up-to-date knowledge to provide clinicians with practical guidance for the management of patients with adrenal incidentalomas. Authors: Martin Fassnacht, Stylianos Tsagarakis, Massimo Terzolo, Antoine Tabarin, Anju Sahdev, John Newell-Price, Iris Pelsma, Ljiljana Marina, Kerstin Lorenz, Irina Bancos, Wiebke Arlt, Olaf M Dekkers Endorsed by: Endocrine Society

European Society of Endocrinology Clinical Practice Guideline: Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition

Authors: Eystein S Husebye, Frederik Castinetti, Sherwin Criseno, Giuseppe Curigliano, Brigitte Decallonne, Maria Fleseriu, Claire E Higham, Isabella Lupi, Stavroula A Paschou, Miklos Toth, Monique van der Kooij, Olaf M Dekkers

European Society of Endocrinology Clinical Practice Guideline on Functioning and non-functioning pituitary adenomas in pregnancy

Authors: A Luger, LHA Broersen, NR Biermasz (ENEA), BMK Biller (ES), M Buchfelder, P Chanson, JOL Jorgensen, F Kelestimur, S Llahana, D Maiter, G Mintziori, F Petraglia, R Verkauskiene (ESPE), SM Webb (Endo-ERN), OM Dekkers Endorsed by: Endocrine Society

European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity

Authors: R Pasquali, F Casanueva, M Haluzik, L van Hulsteijn, S Ledoux, M P Monteiro, J Salvador, F Santini, H Toplak and O M Dekkers

European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors

Clinical Leads: Professor Martin Fassnacht, from University of Würzburg in Germany, and Professor Massimo Terzolo, from University of Turin in Italy

European Society of Endocrinology Clinical Practice Guidelines for the management of Aggressive Pituitary Tumours and Carcinomas

Pituitary tumours are common and easily treated by surgery or medical treatment in most cases. However, a small subset of pituitary tumours does not respond to standard medical treatment and presents with multiple local recurrences (aggressive pituitary tumours) and in rare occasion with metastases (pituitary carcinoma). The present European Society of Endocrinology (ESE) guideline aims to provide clinical guidance on diagnosis, treatment and follow-up in aggressive pituitary tumours and carcinomas.

European Society of Endocrinology Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting

A comprehensive, international guideline that incorporates the most up-to-date knowledge on diagnosis, treatment and patient impact of Turner syndrome (TS) has been published in the European Journal of Endocrinology (EJE). The guidelines incorporate the latest evidence-based advice for diagnosis and treatment of girls and women with TS.

European Society of Endocrinology Clinical Practice Guideline for long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma

Clinical lead: Pierre-Francois Plouin, France. Methodological lead: Olaf M Dekkers, The Netherlands

European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults

Clinical lead: Jens Bollerslev, Norway. Methodological lead: Olaf M Dekkers, The Netherlands

European Society of Endocrinology Clinical guideline for the management of hyponatraemia

Developed by: The European Society of Endocrinology, the European Society of Intensive Care Medicine (ESICM), and the European Renal Association – European Dialysis and Transplant Association.

External Guideline: Semaglutide and cardiovascular outcomes in patients with type 2 diabetes

External Guideline: Liraglutide and cardiovascular outcomes in type 2 diabetes

External Guideline: Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

External Guideline: Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis

External Guideline: Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group

External Guideline: Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes

External Guideline: 2017 Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum

External Guideline: SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of pituitary apoplexy in adult patients

External Guideline: Pharmacological management of obesity: an Endocrine Society clinical practice guideline

External Guideline: Childhood thyroid function, body composition and cardiovascular function

External Guideline: The 2016 European Thyroid Association/European Group on Graves' Orbitopathy Guidelines for the Management of Graves' Orbitopathy

External Guideline: The 2015 European Thyroid Association guidelines on diagnosis and treatment of endogenous subclinical hyperthyroidism

External Guideline: Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline

External Guideline: ENETS consensus guidelines update for gastroduodenal neuroendocrine neoplasms

External Guideline: MANAGEMENT OF ENDOCRINE DISEASE: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis

External Guideline: MECHANISMS IN ENDOCRINOLOGY: Towards the clinical translation of stem cell therapy for type 1 diabetes

External Guideline: A systematic review of recent clinical practice guidelines and best practice statements for the evaluation of the infertile male

External Guideline: ENETS consensus guidelines update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine tumours

External Guideline: Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

External Guideline: Management guidelines for children with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on pediatric thyroid cancer

External Guideline: Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials

External Guideline: Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm–2016 executive summary

External Guideline: ENETS consensus guidelines for high-grade gastroenteropancreatic neuroendocrine tumors and neuroendocrine carcinomas

External Guideline: American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity

External Guideline: American Association of Clinical Endocrinologists, American College of Endocrinology, and Associazione Medici Endocrinologi Medical Guidelines for Clinical practice for the diagnosis and management of thyroid nodules–2016 update

External Guidelines: American Association of Clinical Endocrinologists and American College of Endocrinology–clinical practice guidelines for developing a diabetes mellitus comprehensive care plan–2015

External Guidelines: 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: What is new and what has changed?

External Guideline: Clinical guidelines for management of bone health in Rett syndrome based on expert consensus and available evidence

External Guideline: Gestational diabetes: A clinical update

External Guideline: Role of hepatic intra‐arterial therapies in metastatic neuroendocrine tumours (NET): guidelines from the NET‐Liver‐Metastases Consensus Conference

External Guideline: Revisiting KDIGO clinical practice guideline on chronic kidney disease—mineral and bone disorder: a commentary from a Kidney Disease: Improving Global Outcomes controversies conference

External Guideline: The association of autoimmune thyroid disease (AITD) with psoriatic disease: a prospective cohort study, systematic review and meta-analysis

External Guideline: Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours)

External Guideline: Diagnosis and treatment of Merkel cell carcinoma. European consensus-based interdisciplinary guideline

External Guideline: EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

External Guideline: Population‐relevant endpoints in the evaluation of endocrine‐active substances (EAS) for ecotoxicological hazard and risk assessment

External Guideline: Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine‐active substances

External Guideline: Changing trends in the incidence of thyroid cancer in the United States

External Guideline: Treatment of Cushing's syndrome: an endocrine society clinical practice guideline

External Guideline: Is the endocrine research pipeline broken? A systematic evaluation of the Endocrine Society clinical practice guidelines and trial registration

External Guideline: Vitamin D supplementation guidelines

External Guideline: Androgen-responsive non-coding small RNAs extend the potential of HCG stimulation to act as a bioassay of androgen sufficiency

External Guideline: Shared decision making in endocrinology: present and future directions

External Guideline: 2016 American thyroid association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis

External Guideline: Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations

External Guideline: MANAGEMENT OF ENDOCRINE DISEASE: l-Thyroxine replacement therapy in the frail elderly: a challenge in clinical practice

External Guidelines: Interdisciplinary care in disorders/differences of sex development (DSD): The psychosocial component of the DSD—Translational research network

External Guideline: Consensus recommendations for the diagnosis and management of pancreatic neuroendocrine tumors: guidelines from a Canadian National Expert Group

External Guideline: Which patient-and physician-related factors are associated with guideline adherent initiation of adjuvant endocrine therapy? Results of the prospective multi-centre cohort study BRENDA II

External Guideline: Pediatric obesity—assessment, treatment, and prevention: an Endocrine Society Clinical Practice guideline

External Guideline: DIAGNOSIS OF ENDOCRINE DISEASE: Diagnostic approach to TSH-producing pituitary adenoma

External Guideline: Peer-reviewed and unbiased research, rather than ‘sound science', should be used to evaluate endocrine-disrupting chemicals

External Guideline: American association of clinical endocrinologists and American college of endocrinology disease state clinical review: A neuroendocrine approach to patients with traumatic brain injury

External Guideline: MANAGEMENT OF ENDOCRINE DISEASE: Suicide risk in patients with diabetes: a systematic review and meta-analysis

External Guideline: Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma: the American Thyroid Association Guidelines Task Force on medullary thyroid carcinoma

External Guideline: The American Association of Endocrine Surgeons guidelines for definitive management of primary hyperparathyroidism

External Guideline: American association of clinical endocrinologists and American college of endocrinology disease state clinical review: postoperative management following pituitary surgery

External Guideline: European guidelines for obesity management in adults

Endorsed Guideline: European Academy of Andrology (EAA) guidelines* on investigation, treatment and monitoring of functional hypogonadism in males

Authors: Giovanni Corona, Dimitrios G. Goulis, Ilpo Huhtaniemi, Michael Zitzmann, Jorma Toppari, Gianni Forti, Dirk Vanderschueren, Frederick C. Wu

European academy of andrology guidelines on Klinefelter Syndrome: Endorsing Organization: European Society of Endocrinology

Authors: Michael Zitzmann, Lise Aksglaede, Giovanni Corona, Andrea M. Isidori, Anders Juul, Guy T'Sjoen, Sabine Kliesch, Kathleen D'Hauwers, Jorma Toppari, Jolanta Słowikowska-Hilczer, Frank Tüttelmann, Alberto Ferlin